Do mitochondria care about insulin resistance? (2)
Dr. Chrysi Koliaki will present her last studies published in Molecular Metabolism.
In the last issue of Molecular Metabolism, Dr. Chrysi Koliaki addressed the intensively debated term “mitochondrial dysfunction” in the context of insulin resistance using a comprehensive cell-autonomous approach, which allowed constant substrate delivery to distinct insulin-sensitive cell types circumventing confounding effects of in vivo inter-tissue crosstalk.
The dream of clean and intact mitochondria
The scientific committee invited Dr. Hans Zischka to present his excellent work.
Mitochondrial research indispensably relies on investigations of isolated biochemically intact organelles. However, standard methods lack precisely adjustable and reproducible settings for cell disruption, the initial and most important step in the isolation procedure of mitochondria.
Novel way blocks tumour growth into cancer
Targeting Mitochondria Scientific Committee invited Paolo E. Porporato to present his work about mitochondria and cancer.
In pioneering research on models of human tumours in mice, researchers have successfully blocked metastasis - the strategy adopted by tumour cells to transform into an aggressive form of cancer.
According to researchers from Universite catholique de Louvain (UCL) in Belgium, blocking metastasis or even prevent their formation would be a giant step in the fight against cancer.
The researchers achieved this feat by studying mitochondria in tumour cells. These organelles are considered the cells' powerhouse.
"When their functioning is altered, the mitochondria can promote cell migration, thus leading to the formation of metastasis," said Post-doc Paolo E. Porporato from Universite catholique de Louvain's Institute of Experimental and Clinical Research (IREC). Sonveaux's team examined the molecular mechanism responsible for the mitochondria's ability to promote metastasis.
They succeeded in showing that under certain conditions, the mitochondria produce more free radicals known as superoxide ions. It is this overproduction of superoxide that leads to the formation of metastasis and, consequently, the growth of a tumour, they found.
"The production of superoxide by mitochondria can be blocked by very specific antioxidants," Sonveaux added. These compounds turned out to be very efficient at blocking the migration of tumour cells and preventing the spontaneous formation of human tumour metastasis in mice, the study, published in the journal Cell Reports, said.
Post-doc Paolo E. Porporato will present his strategic studies during targeting Mitochondria 2014
Targeting Mitochondria World Congress 2014 is already a Huge Success
For this new edition of Targeting Mitochondria World Congress, Hotel Ritz Carlton will open its door from October 29 to 31, 2014 to gather more than 400 participants for three days coming from all around the world.
To access to the updated list of participants, please click here.
Come and Network with Targeting Mitochondria participants by registering to the congress here.
Stem cells overcome damage in other cells by exporting mitochondria
The scientific committee invited Dr. Anurag Agrawa to present his excellent work.
He identified a protein that increases the transfer of mitochondria from mesenchymal stem cells to lung cells. In work published in The EMBO Journal, the researchers reveal that the delivery of mitochondria to human lung cells can rejuvenate damaged cells.
The migration of mitochondria from stem cells to epithelial cells also helps to repair tissue damage and inflammation linked to asthma-like symptoms in mice.
Viral Hepatitis and Mitochondrial Dynamics will be highlighted by Pr Aleem Siddiqui
Pr Aleem Siddiqui, from Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA, will highlight the relation between Viral Hepatitis and Mitochondrial Dynamics during Targeting Mitochondria World Congress 2014.
Microbiota & Mitochondria: The Intriguing Relationship
Microbiota & Mitochondria: A Promising Target
The scientific committee will discuss the axes of the next upcoming Targeting Mitochondria World Congress 2014. One of the strategic axes will be Modulation Diversity & Variety of Microbiota by Mitochondria.
Cutaneous respirometry in healthy volunteers: a novel technique for monitoring mitochondrial function awarded by Targeting Mitochondria Scientific Committee
Dr Floor Harms, from Department of Anesthesiology, Laboratory of Experimental Anesthesiology, Erasmus MC – University Medical Center Rotterdam, The Netherlands was awarded by Scientific Committee of Targeting Mitochondria 2013, for her researches about Cutaneous respirometry in healthy volunteers: a novel technique for monitoring mitochondrial function.
The 4th edition of Targeting Mitochondria World Congress was a huge success
Targeting Mitochondria 2013 was a huge success. More than 140 attendees coming from France, Spain, italy, UK, Japan, Denmark, USA, Switzerland... and working for industries and academies gathered in Berlin last October 17-18, 2013.
More than 30 speakers discussed about the recent advances in researches about mitochondria, devices and clinical studies.
The abstracts book of the conference is now available. If you want to order it, please contact us: https://targeting-mitochondria.com/contact-us
Press Release for Immediate Release: Berlin Targeting Mitochondria World Congress reached a record of participants from pharma, biotech industries and academics
Berlin, October 10, 2013
The scientific committee of the 4rd World Congress on Targeting Mitochondria which will be held in Berlin in October 17-18, 2013 published the final agenda and abstracts accepted for oral and poster presentations.
The final agenda of Targeting Mitochondria 2013, Berlin-Germany is now available
On behalf of Scientific Committee, Pr Edeas and Pr Weissig, we are pleased to announce the final agenda of Targeting Mitochondria 2013, which will be held in Berlin, next October 17-18, 2013.
To access to this final agenda, please click here.
Abstract Submission Deadline Extended for Posters Presentation until Friday, September 27 for Targeting Mitochondria 2013
The deadline for submissions for posters presentation has been extended to 27th September, 2013.
Send your abstract for poster presentation by Friday, September 20 (23:59) and may you will win a free registration for Targeting Mitochondria 2013
- Win a Free Registration for Targeting Mitochondria 2013 -
Microbiota, Intestinal Redox Biology & Mitochondria: A Promising Target - A strategic topic to be discussed during Targeting Mitochondria 2013
Microbiota & Mitochondria: A Promising Target
The scientific committee will discuss the axes of the next upcoming Targeting Mitochondria WorldCongress 2014. One of the strategic axes will be Modulation Diversity & Variety of Microbiota by Mitochondria.
Mitochondria & Liver: State of the Art & Perspectives - Hot Topic presented by Pr Rifaat Safadi during Targeting Mitochondria 2013
Pr Rifaat Safadi, Director of Liver Unit, Gastroenterology Institution, Division of Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel wil introduce and chair the special session dedicated to Liver & Mitochondria.
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- Pr Timothy Cheetham, from Newcastle University, witll talk about Mitochondria, Muscle and Vitamin D during Targeting Mitochondria World Congress 2013
- Come & Join the 4rd World Congress on Targeting Mitochondria and meet high quality speakers and Key Leaders Opinion in Mitochondria Research and Innovations
- Among Short Oral Presentations already accepted
- Targeting SK2 mitochondrial channels: A Promising Target for Neuroprotective Strategies
