Cutaneous respirometry in healthy volunteers: a novel technique for monitoring mitochondrial function awarded by Targeting Mitochondria Scientific Committee
Dr Floor Harms, from Department of Anesthesiology, Laboratory of Experimental Anesthesiology, Erasmus MC – University Medical Center Rotterdam, The Netherlands was awarded by Scientific Committee of Targeting Mitochondria 2013, for her researches about Cutaneous respirometry in healthy volunteers: a novel technique for monitoring mitochondrial function.
About the study:
The PpIX triplet state lifetime technique (PpIX-TSLT) has been proposed as a potential clinical non-invasive tool for monitoring mitochondrial function. In vivo mitochondrial respirometry allows measurement of mitochondrial oxygen tension (mitoPO2) and mitochondrial oxygen consumption (mitoVO2) in skin. The principle has been tested in experimental animals. Here we describe the first results of our new clinical prototype in a study in healthy human volunteers.
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