Exploring Mitochondria-Containing Extracellular Vesicles in Alzheimer’s Disease Wins WMS Best Poster Presentation (2)
Congratulations to Tingting Chen from the University of Groningen, Netherlands, for receiving the Best Poster Presentation Award at the 15th Annual World Congress on Targeting Mitochondria!
Her groundbreaking research investigates mitochondria-containing extracellular vesicles (mitoEVs) and their role in Alzheimer's disease (AD).
Chen’s study involved isolating mitoEVs from neural progenitor cells (NPCs) derived from an AD patient with a PSEN1 mutation and comparing them with control cells. While no significant differences were observed in protein concentrations or particle sizes, proteomic analysis revealed a greater diversity of proteins in control EVs.
These findings provide new insights into mitochondrial changes in AD, potentially pointing toward novel therapeutic targets.
