Winner of the Best Mitochondria Image 2022: Erminia Donnarumma, Institut Pasteur

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The World Mitochondria Society congratulates the winner of the Best Mitochondria Image 2022 Erminia Donnarumma, Institut Pasteur, France. Her image entitled "Mitochondria run parallel in mature cardiomyocytes" shows: Adult primary cardiomyocytes (mouse) stained with TMRE (mitochondria, orange) and NucBlue (nuclei, blue).

Dr. DonnarummaDr. Donnarumma performed her PhD (2012-2015) in Pharmaceutical Sciences between the University of Naples Federico II in Italy and the Cardiovascular Center of Excellence in New Orleans (USA). Her work focused on the identification of new medications that could act or improve the crosstalk between the hydrogen sulfide (H2S) and nitric oxide (NO) signaling in small and large animal models of heart failure induced by myocardial ischemia and reperfusion injury. After this time, she nucleated my interest in mitochondria as therapeutic target in cardiac diseases. She therefore moved to France in 2016 to join the Wai Lab at the Institut Pasteur.

Dr. Donnarumma stated: "The main focus of my work was to investigate the role of Mitochondrial Fission Process 1 (MTFP1) in mitochondrial dynamics and the heart homeostasis. I discovered that MTFP1 loss in cardiomyocytes impairs mitochondrial inner membrane integrity leading to impaired mitochondrial bioenergetics, cardiomyocyte death and inflammatory dilated cardiomyopathy. My on-going and future researches aim at the understanding how mitochondria trigger inflammation in cardiomyocytes and the relevance of the sex bias that exists at the level of mitochondria for the development of sex- specific cardiac diseases".

 You will be able to submit your images for #BestMitochondriaImageContest 2023 shortly.

World Mitochondria Society
14th Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany 
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Steigenberger Hotel Am Kanzleramt: Venue of Targeting Mitochondria 2023


The 14th World Congress on Targeting Mitochondria on October 11-13, 2023 in

Steigenberger Hotel Am Kanzleramt
Ella-Trebe-Straße 5
10557 Berlin, Germany

Special offer for Room Booking at Steigenberger Hotel Am Kanzleramt

The WMS committee offers to the congress attendees a preferential rate for the booking. 

Single Superior Room: €189  per night  
Double Superior Room: €209  per night
You can book your room with a preferential rate until September 13.

To remove the city tax, please check 'I am travelling for work'

These rooms are inclusive of taxes, and are 29-34 sqm, modern design located on the 2nd to 5th floors, and include a flat-screen TV, complimentary wireless internet access, air-conditioning, Nespresso machine as well as 1 bottle of mineral water free of charge.
For further inquiries, you can contact the hotel:
  • Via email on This email address is being protected from spambots. You need JavaScript enabled to view it.
  • By phone: +49 30 740 743 990
  • Or by fax: +49 30 740 743 816

You can let them know that you are attending Targeting Mitochondria 2023. You can also use the code "WMS2023" in your communication with them.

World Mitochondria Society
14th Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany

Professor Vladimir Skulachev, 87 years old – All our Condolences

Prof. Skulachev 2023Sad news came from Russia. On February 5, prominent scientist Academician Vladimir Skulachev passed away at the age of 87. He was internationally renowned and highly respected mitochondriologist because of his groundbreaking research in bioenergetics.

Vladimir Skulachev graduated from the biology and soil faculty of Moscow State University (1957), where he has been working since 1960. In 1961 he defended his Ph.D. thesis "The ratio of oxidation and phosphorylation in the respiratory chain."

In 1965-1973 he was the head of the bioenergy department of the Interfaculty Laboratory of Bioorganic Chemistry, since 1973 he was the head of the Laboratory of Bioorganic Chemistry.

In 1991, he became the Director of the Institute of Physical and Chemical Biology named after Belozersky.

In 2002, he founded the Faculty of Bioengineering and Bioinformatics at the Moscow State University and has been its dean to this day.

Among his scientific interests were the mechanisms of biological oxidation, transformation of chemical energy into electrical energy on mitochondrial membranes, the role of membrane potential as a factor conjugating the release and accumulation of energy in the cell. Since 2005, he has been leading a project to create a geroprotector drug based on mitochondria-targeted antioxidants.

Vladimir Skulachev, together with Efim Lieberman, obtained one of the first experimental proofs of the Mitchell’s chemiosmotic theory (Skulachev V.P., Sharaf A.A., and Liberman E.A. // Nature. 1967. V.216. N.5116. P.718-719). Using lipophilic cations and anions, they showed that energized mitochondria can accumulate cations, while submitochondrial particles, anions. In addition to the importance of the results obtained, in this work, the term "protonophore" was first introduced into the scientific literature, which is successfully used to this day. This publication was received with great interest by the scientific community and in recognition of its importance, these ions were named "Skulachev ions” by the famous American biochemist David Green. For this work, in 1975 Vladimir Skulachev was awarded the State Prize of the USSR.

Vladimir Skulachev was a Full member of the Russian Academy of Natural Sciences, member of the European Academy and president of the club of its Russian members, president of the All-Russian Biochemical Society, honorary president of the All-Russian Society of Biochemists and Molecular Biologists, full member of the Academy of Creativity; doctor honoris causa of Vilnius University.

From the first Congress “Targeting mitochondria” in the year 2010, he was a member of the scientific committee and its regular speaker. He regularly took part in the World Mitochondria Society's strategic discussions about the future of mitochondria in health and the strategies on how to progress in this subtle field.

On behalf of the WMS, Volkmar Weissig (President), Marvin Edeas (Founder), and Vladimir Gogvadze (Chairman of the board), we share our all sadness and sympathy with his family and colleagues.

The next meeting on Targeting Mitochondria will be dedicated to Professor Skulachev's legacy in the world of mitochondria. 

Prof. Volkmar Weissig: Editor in Chief at the "Journal of Mitochondria, Plastids and Endosymbiosis"

Journal of Mitochondria Plastids and Endosymbiosis

We would like to anounce that the president of WMS, Prof. Volkmar Weissig, is now serving as one Editor-in-Chief in the new journal by Taylor & Francis "Journal of Mitochondria, Plastids and Endosymbiosis" along with  Prof. Dario Leister, Munich, Germany.

We also mention the associate editors:

Prof. Alessandro Prigione - Heinrich Heine University, Germany
Prof. Alisdair Fernie - Max Planck Insitute of Plant Physiology, Germany
Prof. Kelvin Yen - Leonard Davis School of Gerontology, USA
Prof. Marvin Edeas - Université de Paris, INSERM, France
Prof. Sally Mackenzie - Penn State, Huck Insitutes of Life Sciences, USA
Prof. Virginia Weis - Oregon State, USA
Prof. Vyacheslav Jurchenko - University of Ostrava, Czechia
Prof. Christian Schmitz-Linneweber - Humboldt Univeritat zu Berlin, Germany
Prof. Toshiharu Shikanai - Kyoto University, Japan
Prof Iris Finkemeier - WWU Münster, Germany

This journal is dedicated to serving the biology community by publishing novel and exciting findings with high significance in the biology of mitochondria, plastids and endosymbiosis. It focuses broadly on cellular biology, physiology, biochemistry, molecular biology, genetics, development, genomics, biomedicine, pharmacology, toxicology, bioinformatics, and molecular evolution, as well as on organismic interactions relevant in the context of endosymbiosis. Prof. Weissig will be covering the mitochondria in the endosymbiotic journal section.

Prof. Marvin Edeas, Founder of WMS, Université de Paris, INSERM, stated that: "The World Mitochondria Society will try to connect tightly with the Journal of Mitochondria, Plastids and Endosymbiosis to disseminate the meetings information and activities".

The journal is now open for submission. You can find more details here.

World Mitochondria Society
Website | LinkedIn | Facebook

World Mitochondria Society: Collecting Memories 2022

WMS picture

On behalf of the World Mitochondria Society, we would like to let you know that the Targeting Mitochondria 2022 memories are now accessible. Please find the images here.


Nominations for The Best Mitochondria Image 2022

Best WMS Image 2022

The World Mitochondria Society Scientific Committee will keep accepting images until the end of December 2022! Submit a memorable Mitochondria Image you’ve taken this past year and get the chance to win a free registration for Targeting Mitochondria 2023. Image submissions guidelines.

Images will be shared on the World Mitochondria Society Linked In page. You can vote for your favorite image by pressing the like button. You can find all the nominated images below.


Mitochondrial Crystals

By Catherine Griffiths, Biomedical Imaging Unit Southampton

Catherine Griffiths- Best Mitochondria Image 2022 1

 Mitochondrial fireworks – The Ring of Fire

By Simon Licht-Mayer, Institute of Molecular Biotechnology of the Austrian Academy of Sciences

Simon Licht-Mayer Best Mitochondria Image

Dorsal root ganglia neurons stained for Neurofilament heavy chain (NF200, green), isolectin B4 (IB4, red), calcitonin gene-related peptide (CGRP, cyan), cytochrome c oxidase I (COX-I, orange)

Ultrastructural Resolution of Different Mitochondrial Compartments

By Tasnim Arroum, Westfälische Wilhelms-University Münster

TASNIM ARROUM - Best mitochondria image 2


By Therese Kichuk, PhD Student in Molecular Biology at Princeton University

Therese Kichuk Best Mitochondria Image

This image shows clusters of the budding yeast Saccharomyces cerevisiae. Mitochondria are shown in green and the endoplasmic reticulum is shown in red. 

 Reshaping of Mitochondria During Diabetes

By Licia Anna Pugliese and Luca PesceNEST ( National Enterprise for nanoScience and nanoTechnology),Scuola Normale Superiore

Licia Anna Pugliese Best Mitochondria Image

Confocal microscopy image showing cytokine-treated Ins-1E cells (on the right) and healthy cells (on the left) after staining with the specific marker for mitochondrial outer membrane TOM20 (red), and DAPI for nucleus (blue) to analyze the mitochondrial structure.  The images were taken through a new super resolution method called Expansion Microscopy. Scale bar: 20 μm.

   MiRNA-Dependent Regulation of NAFLD Pathogenesis with Emphasis on the Mitochondrial Aspect

By Maria Bograya, Center for Immunology and Cellular Biotechnology, Immanuel Kant Baltic Federal University

 Maria Bograya

  When Mitochondria Loves You Back

 By Tanoy Dutta, Department of Chemistry, Indian Institute of Science Education and Research

Tanoy Dutta Best Mitochondria Image

Confocal microscopy image showing a U-87 MG cell stained with a mitochondria-targeting small molecule organic fluorophore Quinaldine Red to study the mitochondrial dynamics

 Mitochondrial Red Eye

by Agnieszka Fedoruk-Wyszomirska, Institute of Bioorganic Chemistry, Polish Academy of Sciences

Agnieszka Fedoruk-Wyszomirska Best Mitochondria Image 2

Confocal microscopy image showing the mitochondrial network, cytoskeleton, and nucleus in MRC5 cell after FC treatment stained with MitoTracker Red CMXRos, Alexa Fluor 488 phalloidin, and Hoechst 33342, respectively.

 Uncovering Where the Mitochondrion Makes its Proteins

By Rolando Berlinguer Palmini and Matt Zorkau, Newcastle University

Dr. Rolando Berlinguer Palmini and Dr. Matt Zorkau Best Mitochondria Image

Synthesis of mitochondrial-encoded proteins in U20S cells was labelled with the methionine analogue HPG and detected by a fluorescent azide (green). Mitochondrial inner boundary membranes (magenta) were visualised by immunofluorescent labelling of Tim23. Stimulated emission depletion (STED) microscopy and surface rendering was used to determine sub-mitochondrial resolution of the targets.

 MIRO1 Regulates Mitochondrial Trafficking in Cancer-Associated Fibroblasts 

By Michael Cangkrama, ETH Zurich

Michael Cangkrama Best Mitochondria Image

MIRO1 labeling in the mitochondrial network of skin fibroblasts

 Mitochondrion Before Oxaliplatin Storm

By Toni Martinez-Bernabe, University of Balearic Islands

TONI MARTINEZ-BERNABE Best Mitochondria Image


By  Valentin Baumgartner, PhD student at the Laboratory for Urologic Oncology and Stem Cell Therapy, University Hospital Zurich

Valentin Baumgartner Best Mitochondria Image

PC-3 prostate cancer cells were stained with TOM20 to analyse the mitochondrial network. Depicted here is one “Megacell” entangling other cells with its extensive mesh of mitochondria.

The Beauty & the Beast

By Arpit Mehrotra and Deepak Kumar Sharma,  Council of Scientific & Industrial Research-Institute of Microbial Technology, India


SH-SY5Y cells were stained with Mitotracker-RED dye (in Red) and Hoechst dye (in Blue) to track mitochondrial networking in control (A) and synuclein transfected (B) cells, wherein beauty of mitochondrial networking was observed in control and the synuclein mediated beastly-broken network was observed upon its overexpression. Scale bar-20µm

Mitochondria run parallel in mature cardiomyocytes

By Erminia Donnarumma, Institut Pasteur, France


Adult primary cardiomyocytes (mouse) stained with TMRE (mitochondria, orange) and NucBlue (nuclei, blue). 

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany

Dr. Ian Holt was Discerned the Best Scientific Award 2022

Ian Holt V1 - copie


The World Mitochondria Society awarded Dr. Ian J. Holt, Instituto de Investigación Sanitaria Biodonostia, Spain for his scientific contribution 2-Deoxy-D-Glucose Couples Mitochondrial DNA Replication with Mitochondrial Fitness.

Dr. Holt shared his future goals with the scoentific committee: "Continuing the collaboration with Professor Spinazzola (University College London), we have developed comprehensive future plans, which have attracted new funding".

Dr. Holt's future plans include: 

  • launching the first clinical trial of 2DG late in 2023 in patients carrying the m.3243A>G mutation; 
  • testing 2DG against other heteroplasmic variants, including in a heteroplasmic mouse model (m.5024C>T)
  • assessing the effect of the compound on other cell types; and finally
  • elucidating further how nutrient and metabolite availability affect mitochondrial DNA replication and selection. 

 Dr. Holt stated: "These are exciting times for us and we hope to be able to share our substantial progress with you next year."

In case you missed Targeting Microbiota 2022 meeting, you can demand for the recordings/abstract book access.

 Listen to Dr. Holt's Talk

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany

Dr. John Ball was Awarded for His Innovation During Targeting Mitochondria 2022

John Ball V1

John Ball 2

 Dr. John Ball, National Eye Institute (NEI), The National Institutes of Health (USA) received the Targeting Mitochondria Best Innovation Award. His innovative work on Mitochondria in Retinal Photoreceptors: More than Meets the Eye was awarded.

Dr. Ball stated: "The finding that mitochondria in retinal photoreceptors have a prominent optical role provides a promising avenue to connect photoreceptor bioenergetics with noninvasive retinal imaging. To this end, we are currently developing our electromagnetic simulations to capture the influence of photoreceptor mitochondria on clinical imaging, and we plan to examine the connections between mitochondrial function and their optical characteristics."

In case you missed the conference, you can still benefit from a 3 weeks access to Targeting Mitochondria 2022 presentations

Watch Dr. Ball's Presentation

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany

Short Oral Presentation Award 2022: Intra-Articular Injection of Mitochondria to Treat Osteoarthritis

Mercedes Fernandez-Moreno 2Mercedes Fernandez-Moreno, Instituto de Investigación Biomédica de A Coruña (INIBIC), Spain, was discerned the best short oral presentation award for her innovative talk on the Approach for Using Intra-Articular Injection of Mitochondria to Treat Osteoarthritis.

Nowadays there is not cure or an efficient treatment for osteoarthritis (OA), despite of its the most common rheumatology illness and a major cause of pain and disability in older adults. The relation between mitochondria alteration and OA was described in several studies in which the authors explained how mitochondrial alteration can modulate the chondrocyte function and its survival during this pathogenesis

Mitochondria have proposed as a potential therapeutic target for OA. Dr. Fernandez-Moreno and her team hypothesized that transplantation of heterologous mitochondria from healthy donor would ameliorate the OA effects. The analysis of in vivo model showed that mitochondria injection was safety and no inflammatory response was observed in the joint. These preliminary data gave them the possibility to continue studying the mitochondrial transplantation as an efficient treatment for OA.

Dr. Fernandez-Moreno stated to the World Mitochondria Society: "Taken into account our preliminary data, we will continue in the develop of more robust data generating a complete in vivo model to confirm the role of healthy mitochondria over the OA cartilage."

In case you missed Dr. Fernandez-Moreno's winning presentation, you can access the conference material here.

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany

Targeting Mitochondria 2022 Best Poster Presentation Awards


The #WorldMitochondriaSociety Scientific Committee awarded three poster presenters for the insightful research and strategic results that they presented during Targeting Mitochondria 2022. We will be looking forward to learning about their progress during the next edition. 

Daniel Szames - Poster award 2022 2 

Peptide Mediated Mitochondrial Delivery of Temozolomide for Evading Cellular Resistance Mechanism
Daniel Szames, University of Toronto, Canada

Daniel Szames commented: "Future work involving mitochondria-targeted temozolomide include further exploring the therapeutic potential as well as exploring its use as a DNA-damage repair probe. The use of patient-derived glioblastoma stem cells will act as a relevant model to determine whether mitochondria-targeted temozolomide has clinical potential. This compound can also be used to investigate the role of other DNA-damage repair mechanisms in mitochondria; for example, to investigate the role of mismatch repair in mitochondria."

 Sophie Dhorne-Pollet Poster award 2022 2 Mitochondrial Genomes Long Read Sequencing Methodology Applied to Multispecies for the Identification of Genetic Variants
Sophie Dhorne-Pollet, Université Paris-Saclay, INRAE, France
 Mina Lim Poster Award 2022 2  

Mitochondria Enriched NK Cell Therapy for Solid Tumors
Mina Lim, CHA University 차의과학대학교, Republic of Korea

If you wish to review these posters, you can order the abstracts here.

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany

Targeting Mitochondria 2022 Online Posters


Please find here all Online posters presented during the Targeting Mitochondria 2022 Congress. The abstract of each poster is included in Abstracts Book of congress.



Did you participate in Targeting Mitochondria 2022?

The all presented major & short oral communications will be available as recorded presentations shortly.

Did not attend but wish to access to the Replay :

To access to the Congress & Workshop recorded presentations and get the Abstracts Book of congress & workshop, please contact us.

Best Mitochondria Image Contest 2022

Best WMS Image 2022

Submit a memorable Mitochondria Image you’ve taken this past year and get the chance to win a free registration for the next congress to be held in 2023! The scientific committee also accept artwork and drawings related to Mitochondria (life, death, energy, dynamics and philosophy...). 

Entries must be original and contestants should be registered to the Targeting Mitochondria 2022 congress. Results will be announced at the begining of 2023.

Image Submission Guidelines

To enter the contest, please make sure to send us the following information on a Word Document:

1. Your name

2. Your complete affiliation

3. A picture of you (optional)

4. Your Mitochondria Image with:

- A title

- The description of the image

- The context of the study


and send it to: This email address is being protected from spambots. You need JavaScript enabled to view it.">This email address is being protected from spambots. You need JavaScript enabled to view it.

 May the best image Win!


Prof. Wallace: Keynote Speaker at WMS 2022

Mitochondria 2022 Mitochondrial Medicine present and future

IIt was a great pleasure to welcome Prof. Douglas C. Wallace, Children's Hospital of Philadelphia, USA, at Targeting Mitochondria 2022 congress. He  introduced the meeting with a keynote speech on Mitochondrial Medicine : Present and Future.

Dr. Wallace is a geneticist and evolutionary biologist who founded the field of mitochondrial medicine 40 years ago. He investigates the role of mitochondria in human evolution, health, and disease.


Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany

Recent Advances in Mitochondrial Transplantation Therapy

Dr James McCullyDr. James D. McCully, from The Harvard Medical School Department of Cardiac Surgery Boston Children’s Hospital, USA, will join us this year to present his most recent findings on "Recent Advances in Mitochondrial Transplantation Therapy".

Join us in Targeting Mitochondria 2022 and benefit from the experience of professional researchers in this field. Book your spot.

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany




Regulation of Mitochondrial DNA Polymerase POLG1 Proteolysis and its Role in the Progeroid Disease Cockayne Syndrome and Physiological Ageing

Miria RicchettiDr. Miria Ricchetti, Institut Pasteur, France will join us this year to present her most recent findings on "Regulation of Mitochondrial DNA Polymerase POLG1 Proteolysis and its Role in the Progeroid Disease Cockayne Syndrome and Physiological Ageing".

The mechanisms of proteolysis and proteostasis of several mitochondrial matrix proteins are known. This was not the case for the pivotal polymerase POLG1 that ensures the replication of the mitochondrial genome. Dr. Ricchetti and her team show here a mechanism that leads to POLG1 degradation and has implications in pathophysiological ageing.

Join us in Targeting Mitochondria 2022 and benefit from the experience of professional researchers like Dr. Ricchetti. Book your spot.

Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany