Mitochondrial Dynamics: Updates and Perspectives
It is a great pleasure to welcome Dr. Ježek Petr, Institute of Physiology of the Czech Academy of Sciences, Czech Republic, at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Mitochondrial Dynamics: Updates and Perspectives.
Highlights
- Mitochondrial network facilitates rejuvenation of fragments and communication via exosomes.
- Mitochondrial cristae morphology changes with metabolism and oxidative phosphorylation (OXPHOS).
- INS-1EΔe+g cells showed lower ATP synthesis, inhibited insulin secretion (IS), and distinct mitochondrial cristae structures.
- Exosomes from stressed pancreatic cells may communicate stress responses.
- Regular mitochondrial cristae can form without major FO subunits of ATP-synthase.
- Delayed mitophagy in IS-impaired cells might lead to exosomes signaling pathology.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
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