The Future of Medicine will come through Mitochondria


Prof. Volkmar WeissigWe are excited to invite you to the 17th World Mitochondria Scoiety's Annual Meeting, happening from October 21–23, 2026, in Berlin. This annual event brings together top experts in mitochondrial research and medicine to share new discoveries and ideas in mitochondrial therapy, gene treatment, and mitochondrial transplantation.

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Targeting Mitochondria 2023 Best Poster Presentation Award for Young Investigator

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It gives us immense pleasure to announce that Tatjana Kuen from Leopold-Franzens Universität Innsbruck, Austria, has been distinguished with the Targeting Mitochondria 2023 Best Poster Presentation Award for Young Investigators.

Her poster, titled "Inhibitors of Fumarylacetoacetate Domain Containing Protein 1 (FAHD1) Induce Premature Cellular Senescence in Human Endothelial Fibroblasts in Vitro," delves into the intricate role of FAHD1 as an oxaloacetate decarboxylase in the TCA cycle regulation. Notably, the findings revealed that a lentiviral knockdown of FAHD1 could lead HUVEC cells into premature cellular senescence. The proposed model suggests a mitochondrial dysfunction-associated senescence-like phenotype that is potentially mediated through the reduction of complex-II activity. Currently, Tatjana and her team are exploring the use of second-generation FAHD1 inhibitors to replicate this intriguing effect.

Join us in extending heartfelt congratulations to Tatjana Kuen for this outstanding achievement.


Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany 
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2023 Best Short Oral Presentation Award

WMS BEST ORAL 1 2023

Targeting Mitochondria 2023 Best Short Oral Presentation Award #1

The World Mitochondria Society congratulate Dr. Ioannis Tsichlis from the National & Kapodistrian University of Athens, Greece, for earning the Best Short Oral Presentation award at Targeting Mitochondria 2023.

Dr. Tsichlis's profound talk, titled "Development of Mitochondria-Inspired Lipopolyplexes for Gene Delivery," was a deep dive into the cutting-edge realm of gene therapy.

He presented a novel mitochondrial-inspired nanosystem, which incorporated the properties of mitochondria into hybrid lipopolyplexes. These meticulously crafted structures are geared towards efficient gene delivery, offering a potential leap in therapeutic interventions. Particularly noteworthy was their remarkable stability across various media, an essential characteristic for real-world applications.

His talk was a testament to his dedication and innovative approach in the field of targeting mitochondria.

Dr. Tsichlis shared with the World Mitochondria Society: "Following the successful development of mitochondria-inspired lipopolyplexes, our research involves in vitro cytotoxicity studies and in vivo biological experiments in the well-established C. elegans model to evaluate the specificity and efficiency of the nanoplatform in targeting mitochondria. The ultimate goal is to develop a safe and effective bio-inspired gene delivery nanoplatform that will contribute to mitochondrial gene therapy."

All our congratulations.


Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany 
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2023 Best Short Oral Presentation Award

WMS BEST ORAL 2 2023

Targeting Mitochondria 2023 Best Short Oral Presentation Award #2

The World Mitochondria Society celebrates Sami Noujaim from the University of South Florida, USA, for clinching the Targeting Mitochondria 2023 Best Short Oral Presentation Award.

Dr. Noujaim's insightful talk, "Mitochondrial Involvement in Cardiac Electrophysiological Injury Due to Inhalation Exposure to Electronic Nicotine Delivery Systems (ENDS)," delved into the alarming effects of vaping on heart electrophysiology.

He expertly highlighted the role of adverse mitochondrial changes and increased oxidative stress in these effects.

All our congratulations.


Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany 
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2023 Best Scientific Contribution Award at Targeting Mitochondria 2023

WMS 2023 SCIENTIFIC CONTRIBUTION 2

Dr. Naig Gueguen from the Mitovasc Institute has been recognized with the coveted 2023 Best Scientific Contribution Award, a testament to her role as a trailblazing scientist in the field.

In her excellent workshop titled "How to Evaluate Mitochondrial Function," Dr. Gueguen, affiliated with INSERM 1083, CNRS 6215, and Centre Hospitalier Universitaire d’Angers, showcased the depth of her expertise.

She navigated through the nuances of mitochondrial study, touched on key technological tools, delved into critical markers, elucidated diverse techniques for examination, presented diagnostic approaches, and shared invaluable case studies centered on mitochondrial anomalies.

The WMS extends its heartfelt congratulations to Dr. Gueguen for her stellar contributions and presentation.


Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany 
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Emerging Trends & Strategies: 15th World Congress 2024

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Join us in Berlin from October 29-31, 2024, for the 15th World Congress on Targeting Mitochondria. 

Targeting Mitochondria 2024: New Visionary Approaches

The President of the World Mitochondria Society, Volkmar Weissig, and the Chairman of the Scientific Board, Marvin Edeas, have highlighted the complexities involved in curating an agenda and identifying suitable speakers as significant challenges. In response, they are adopting a progressive and "out of the box" perspective.

Volkmar Weissig and Marvin Edeas aim to take an unconventional approach by concentrating on Emerging Trends and Strategies in mitochondrial research. To this end, they have selected topics such as exosomes and extracellular vesicles, the application of artificial intelligence, the mitochondria-microbiota interplay, the role of mitochondria in photomedicine, and exploratory discussions on the incorporation of Chinese medicine principles.


Summary of the Agenda

Day 1 - Tuesday, October 29, 2024: Mitochondria Workshop 

  • Workshop Title: “How to Evaluate Mitochondria Function? Bridging Theory and Practice” 
  • Led by: Dr. Naïg Gueguen, MitoVasc Institute, Angers University Hospital Center, France.
  • Focus on methodologies and techniques for assessing mitochondrial function accurately.

Day 2 - Wednesday, October 30, 2024: Keynote and Sessions

Keynote Presentation: “The Mitochondrial Kingdom: Historical Moments, Evolutionary Insights, Current Understanding, and Future Projections.”

Session 1: Mitochondrial Biodynamics in Health and Diseases

  • Topics include mitochondrial mitophagy and biogenesis, mitochondria in cancer, aging, cell communication, and the interconnections between iron, ferritin, and mitochondria.

Session 2: Evaluation and Quality Control of Mitochondrial Function

  • Highlights innovations in mitochondrial function measurement, real-time visualization techniques, new monitoring devices, and quality control mechanisms.

Day 3 - Thursday, October 31, 2024: Continuing Sessions and Concluding Remarks

Session 3: 15th World Mitochondria Society Meeting on Emerging Trends and Strategies

  • Covers exosomes and extracellular vesicles, AI in research, mitochondria-microbiota interplay, updates on mitochondria in photomedicine, and considerations of Chinese medicine.

Session 4: Mitochondrial Medicine 2024: From Bench to Bedside

  • Focuses on practical applications like mitochondrial transplantation, transfer & tunneling nanotubes, pharmaceutical approaches, and the latest clinical studies targeting mitochondria.

Concluding Remarks & Awards:

  • Summarizing key takeaways, next steps in mitochondrial research, and recognizing outstanding contributions.

Learn more about the program.


It will be a great pleasure to meet you in Berlin next October for this exciting congress!

Sincerely,

Prof. Volkmar WeissigProf. Volkmar Weissig
President of the World Mitochondria Society
Midwestern University, USA
On behalf of the WMS Scientific Board

 

DOI Assignment for Targeting Mitochondria 2024 Abstracts

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We are pleased to announce that all abstracts submitted this year to the 15th Annual meeting of the WMS will be included in the Targeting Mitochondria 2024 Abstracts Book, which will be assigned a DOI (Digital Object Identifier). This ensures your work will have a permanent and easily accessible online presence.

Importance of DOI

Having a DOI means your abstracts will be indexed on major academic platforms such as ORCID, Google Scholar, Scopus and others. This not only enhances the visibility of your research but also facilitates easy citation and sharing within the scientific community.

Abstract Submission Details

You can submit your abstracts here: www.wms-site.com/abstract submission

Dr. James McCully will be invited by Dr. Marvin Edeas to highlight Mitochondrial Transplantation on March 22

Webinar Dr. McCully - WMS

Dr. Marvin Edeas, Institut Cochin, INSERM U1016, Université Paris Cité, France, is pleased to invite Dr. James McCully of Harvard Medical School and Boston Children's Hospital to present a talk dedicated to Mitochondrial Transplantation, both online and in Paris.

The focus of the Dr. McCully's talk will be on "Mitochondrial Transplantation: Rescue of Cellular Viability and Function and Modulation of the Ischemic Phenotype in the Myocardium".

Dr. McCully will discuss the role of mitochondrial transplantation in improving outcomes for myocardial ischemia/reperfusion injury and its effects on the transcriptomic profile.

You are all cordially invited to join us.

World Mitochondria Society


Practical Information

Date & Venue

The webinar is scheduled for Friday, March 22, 2024, from 3:00 PM to 5:15 PM Paris time.

Participants can choose to attend the event in two ways:

  • In person at the Université Paris Cité, Institut Cochin - Bâtiment Méchain, Salle Rosalind Franklin, in Paris.
  • Virtually, through a Zoom webinar.

Registration & Participation

There is no fee to attend this webinar, but space is limited. Interested individuals are encouraged to register early to ensure participation.

 

Book your Spot

 


Why did Dr. Marvin Edeas invite Dr. James McCully to host a webinar on Mitochondrial Transplantation?

James McCully 1Dr. McCully plays a strategic role in the field of medicine, especially his groundbreaking work in pediatric cardiac surgery and his development of mitochondrial transplantation. Dr. McCully has dedicated his career to innovating treatment approaches for congenital heart conditions, significantly improving outcomes for pediatric patients. His research has not only advanced surgical procedures but also introduced new technologies to enhance the quality of life for children with heart defects.

The technique of mitochondrial transplantation, pioneered by Dr. McCully, represents a major advancement in medical science, offering a novel method to deliver healthy mitochondria directly to damaged tissues, thus rescuing organ function. This innovation, first applied at Boston Children's Hospital in 2014, has shown that mitochondrial transplantation can safely and effectively restore injured heart muscle, even in critical cases.

Given Dr. McCully's extensive publication record, with 234 papers and 13 patents, and his involvement in leading scientific associations, his expertise and contributions are highly valued by the medical community. His work aligns closely with the interests of the World Mitochondria Society, making him an ideal candidate to share insights on the therapeutic efficacy of mitochondrial transplantation in treating myocardial ischemia/reperfusion injury and its potential for broader applications in medicine.

More about Dr. McCully.

 

 

Evaluation and Quality Control of Mitochondrial Function: Where we are Now & What's Next?

Egbert Mik 1It is a great pleasure to welcome Dr. Egbert Mik, Erasmus MC, The Netherlands, and active member of the WMS scientific committee, at Targeting Mitochondria 2024 this October in Berlin. 

Presentation title: Evaluation and Quality Control of Mitochondrial Function: Where we are Now & What's Next?

About Egbert Mik

Dr. Mik’s research focuses on the development and use of novel techniques to comprehensively measure tissue oxygenation and cellular oxygen utilization in vivo. Microvascular oxygen tension (μPO2) is measured by means of oxygen-dependent quenching of phosphorescence of injectable oxygen-sensitive dyes. Mitochon-drial oxygen tension (mitoPO2) is measured by delayed fluorescence of protoporphyrin IX. Recent technical advances now allow the simultaneous measurement of μPO2 and mitoPO2 in complex animal models. Next to comprehensive tissue oxygen measurements also a method for assessment of mitochondrial respiration in vivo has been developed. The Laboratory of Experimental Anesthesiology now possesses a unique setup for measuring oxygenation and oxygen consumption at the subcellular level in vivo. Topics of interest are mitochondrial dysfunction in sepsis and cellular adaptation to changes in oxygen homeostasis (oxygen conformance of metabolism).
 
Next to the preclinical research Bert Mik developed a clinical device for monitoring Cellular Oxygen METabolism (COMET), based on the delayed fluorescence lifetime technique for mitoPO2 measurements. Commercial versions of COMET have become available in 2016 and several clinical studies in and outside the ErasmusMC are currently being performed.

WMS 2024 Speakers Lineup. 


World Mitochondria Society 
Annual World Congress on Targeting Mitochondria
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