Regulation of Mitochondrial DNA Polymerase POLG1 Proteolysis and its Role in the Progeroid Disease Cockayne Syndrome and Physiological Ageing
Dr. Miria Ricchetti, Institut Pasteur, France will join us this year to present her most recent findings on "Regulation of Mitochondrial DNA Polymerase POLG1 Proteolysis and its Role in the Progeroid Disease Cockayne Syndrome and Physiological Ageing".
The mechanisms of proteolysis and proteostasis of several mitochondrial matrix proteins are known. This was not the case for the pivotal polymerase POLG1 that ensures the replication of the mitochondrial genome. Dr. Ricchetti and her team show here a mechanism that leads to POLG1 degradation and has implications in pathophysiological ageing.
Join us in Targeting Mitochondria 2022 and benefit from the experience of professional researchers like Dr. Ricchetti. Book your spot.
Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany
Recent Advances in Mitochondrial Transplantation Therapy
Dr. James D. McCully, from The Harvard Medical School Department of Cardiac Surgery Boston Children’s Hospital, USA, will join us this year to present his most recent findings on "Recent Advances in Mitochondrial Transplantation Therapy".
Join us in Targeting Mitochondria 2022 and benefit from the experience of professional researchers in this field. Book your spot.
Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany
wms-site.com
Prof. Wallace: Keynote Speaker at WMS 2022
IIt was a great pleasure to welcome Prof. Douglas C. Wallace, Children's Hospital of Philadelphia, USA, at Targeting Mitochondria 2022 congress. He introduced the meeting with a keynote speech on Mitochondrial Medicine : Present and Future.
Dr. Wallace is a geneticist and evolutionary biologist who founded the field of mitochondrial medicine 40 years ago. He investigates the role of mitochondria in human evolution, health, and disease.
Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany
Best Mitochondria Image Contest 2022
Submit a memorable Mitochondria Image you’ve taken this past year and get the chance to win a free registration for the next congress to be held in 2023! The scientific committee also accept artwork and drawings related to Mitochondria (life, death, energy, dynamics and philosophy...).
Entries must be original and contestants should be registered to the Targeting Mitochondria 2022 congress. Results will be announced at the begining of 2023.
Image Submission Guidelines
To enter the contest, please make sure to send us the following information on a Word Document:
1. Your name
2. Your complete affiliation
3. A picture of you (optional)
4. Your Mitochondria Image with:
- A title
- The description of the image
- The context of the study
and send it to: This email address is being protected from spambots. You need JavaScript enabled to view it.">This email address is being protected from spambots. You need JavaScript enabled to view it.
May the best image Win!
Targeting Mitochondria 2022 Online Posters
Please find here all Online posters presented during the Targeting Mitochondria 2022 Congress. The abstract of each poster is included in Abstracts Book of congress.
Did you participate in Targeting Mitochondria 2022?
The all presented major & short oral communications will be available as recorded presentations shortly.
Did not attend but wish to access to the Replay :
To access to the Congress & Workshop recorded presentations and get the Abstracts Book of congress & workshop, please contact us.
Targeting Mitochondria 2022 Best Poster Presentation Awards
The #WorldMitochondriaSociety Scientific Committee awarded three poster presenters for the insightful research and strategic results that they presented during Targeting Mitochondria 2022. We will be looking forward to learning about their progress during the next edition.
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Peptide Mediated Mitochondrial Delivery of Temozolomide for Evading Cellular Resistance Mechanism Daniel Szames commented: "Future work involving mitochondria-targeted temozolomide include further exploring the therapeutic potential as well as exploring its use as a DNA-damage repair probe. The use of patient-derived glioblastoma stem cells will act as a relevant model to determine whether mitochondria-targeted temozolomide has clinical potential. This compound can also be used to investigate the role of other DNA-damage repair mechanisms in mitochondria; for example, to investigate the role of mismatch repair in mitochondria." |
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Mitochondrial Genomes Long Read Sequencing Methodology Applied to Multispecies for the Identification of Genetic Variants Sophie Dhorne-Pollet, Université Paris-Saclay, INRAE, France |
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Mitochondria Enriched NK Cell Therapy for Solid Tumors |
If you wish to review these posters, you can order the abstracts here.
Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany
wms-site.com
Short Oral Presentation Award 2022: Intra-Articular Injection of Mitochondria to Treat Osteoarthritis
Mercedes Fernandez-Moreno, Instituto de Investigación Biomédica de A Coruña (INIBIC), Spain, was discerned the best short oral presentation award for her innovative talk on the Approach for Using Intra-Articular Injection of Mitochondria to Treat Osteoarthritis.
Nowadays there is not cure or an efficient treatment for osteoarthritis (OA), despite of its the most common rheumatology illness and a major cause of pain and disability in older adults. The relation between mitochondria alteration and OA was described in several studies in which the authors explained how mitochondrial alteration can modulate the chondrocyte function and its survival during this pathogenesis
Mitochondria have proposed as a potential therapeutic target for OA. Dr. Fernandez-Moreno and her team hypothesized that transplantation of heterologous mitochondria from healthy donor would ameliorate the OA effects. The analysis of in vivo model showed that mitochondria injection was safety and no inflammatory response was observed in the joint. These preliminary data gave them the possibility to continue studying the mitochondrial transplantation as an efficient treatment for OA.
Dr. Fernandez-Moreno stated to the World Mitochondria Society: "Taken into account our preliminary data, we will continue in the develop of more robust data generating a complete in vivo model to confirm the role of healthy mitochondria over the OA cartilage."
In case you missed Dr. Fernandez-Moreno's winning presentation, you can access the conference material here.
Targeting Mitochondria 2022 Congress
October 26-28, 2022 - Berlin, Germany
wms-site.com
Dr. John Ball was Awarded for His Innovation During Targeting Mitochondria 2022
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Dr. John Ball, National Eye Institute (NEI), The National Institutes of Health (USA) received the Targeting Mitochondria Best Innovation Award. His innovative work on Mitochondria in Retinal Photoreceptors: More than Meets the Eye was awarded. Dr. Ball stated: "The finding that mitochondria in retinal photoreceptors have a prominent optical role provides a promising avenue to connect photoreceptor bioenergetics with noninvasive retinal imaging. To this end, we are currently developing our electromagnetic simulations to capture the influence of photoreceptor mitochondria on clinical imaging, and we plan to examine the connections between mitochondrial function and their optical characteristics." In case you missed the conference, you can still benefit from a 3 weeks access to Targeting Mitochondria 2022 presentations. |
Watch Dr. Ball's Presentation
October 26-28, 2022 - Berlin, Germany
wms-site.com
