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Thank You for Joining WMS Webinar: A Special Thanks to Prof. Howy Jacobs

Webinar

The World Mitochondria Society sincerely thanks you for attending our webinar with Professor Howy Jacobs from Tampere University, Finland. We are especially grateful to Prof. Jacobs for sharing his groundbreaking insights into mitochondrial thermoregulation and its impact on cell biology, evolution, and disease. His presentation has opened new perspectives and challenges our understanding of mitochondrial function.

A special thank you to Prof. Jacobs for his invaluable contribution, and to all participants for being part of this important discussion. We look forward to continuing this exciting journey together!

Dr. Marvin Edeas, Université de Paris, INSERM U1016 Institut Cochin, and Founder of the World Mitochondria Society, shared his thoughts following the webinar:

"After listening to the excellent webinar of Professor Howy Jacobs on mitochondrial thermoregulation, it becomes clear that we must re-evaluate our current understanding of mitochondrial biology. For years, therapeutic strategies have been developed based on the premise that mitochondria operate at typical body temperature (~37°C).

However, if mitochondria actually function closer to 50°C, as you suggest, this changes how we should approach the design and delivery of mitochondria-targeted compounds.

If we fail to adapt our strategies to these new insights, we risk overlooking the true therapeutic power of the mitochondria.

Prof. Jacobs opened a new fascinating door to the world of mitochondria."

 

Watch the recorded Webinar Here.

 
You can also watch the Second Webinar on "Understanding Horizontal Mitochondrial Transfer: The Good and the Bad" by Dr. Andrés Caicedo and Dr. Estefanía Nova Here.


 About Howy Jacobs

Howy Jacobs 1Prof. Howy Jacobs is a globally recognized expert in mitochondrial biology. In his recent work, A Century of Mitochondrial Research, 1922–2022 (Enzymes Book Series, 2023), he explores the fascinating journey of mitochondria—from their early recognition as bacteria-like structures to their pivotal roles in modern cell physiology. His contributions span biochemistry, genetics, pathology, and cell biology, shaping our current understanding of mitochondria.

WMS Speakers 2025

Keynote Speech: Targeting Mitochondrial Channels: Update and Strategies
Keynote Speech: Targeting Mitochondrial Channels: Update and StrategiesAdam Szewczyk, Nencki Institute of Experimental Biology, Poland
Keynote Speech - Mitochondria and the Meaning of Life
Keynote Speech - Mitochondria and the Meaning of LifeNick Lane, University College of London, United Kingdom
Immune Evasion through Tumor-Derived Mitochondrial Transfer
Immune Evasion through Tumor-Derived Mitochondrial TransferYosuke Togashi, Okayama University, Japan
Targeting Mitochondrial Pyruvate Carrier: Impact on Future Metabolic Therapies
Targeting Mitochondrial Pyruvate Carrier: Impact on Future Metabolic Therapies Edmund Kunji, University of Cambridge, United Kingdom
Mitochondrial Dynamics: Steering the Future of Mitochondrial Remodeling in Health and Disease
Mitochondrial Dynamics: Steering the Future of Mitochondrial Remodeling in Health and DiseaseTatjana Kleele, Institute of Biochemistry, ETH Zurich, Switzerland
Nerve-to-Cancer Mitochondrial Transfer: A Key Driver of Metastasis
Nerve-to-Cancer Mitochondrial Transfer: A Key Driver of MetastasisSimon Grelet, Assistant Professor, University of South Alabama, USA
Drug Development for the Therapy of Mitochondrial Diseases
Drug Development for the Therapy of Mitochondrial DiseasesVolkmar Weissig, Midwestern University, College of Pharmacy Glendale, USA
Fighting Fire with Fire: Boosting T Cell Therapy by Intercellular Mitochondrial Transfer
Fighting Fire with Fire: Boosting T Cell Therapy by Intercellular Mitochondrial TransferLuca Gattinoni, Leibniz Institute for Immunotherapy, Germany
Workshop on Mitochondrial Transfer and Transplantation: From Bench to Bedside
Workshop on Mitochondrial Transfer and Transplantation: From Bench to BedsideAndrés Caicedo, Universidad San Francisco de Quito, School of Medicine, Ecuador
Brain Organoids for Drug Discovery of Mitochondrial Neurological Disorders
Brain Organoids for Drug Discovery of Mitochondrial Neurological DisordersAlessandro Prigione, Heinrich Heine University, Germany
Mitochondria and Creatine: Perspectives and Strategies
Mitochondria and Creatine: Perspectives and StrategiesDavid Rizo Roca, Karolinska Institutet, Sweden
Mitochondrial Cybrids: Advancing Precision Oncology
Mitochondrial Cybrids: Advancing Precision OncologyAlberto Anel, University of Zaragoza, Spain

Workshops of Targeting Mitochondria 2025

WMS 2025 SAVE THE DATE

Workshop 1: How to Evaluate Mitochondria Function?
Naïg Gueguen, Mitovasc Institute, Centre Hospitalier Universitaire d'Angers, France

Workshop 2: Mitochondria Transplantation: From Theoretical to Clinical Applications
Andrés Caicedo, Universidad San Francisco de Quito, Ecuador

Read more.

Targeting Mitochondria 2025 Speakers & Sessions

Day 1 - Wednesday October 22, 2025

Workshops

Workshop 1: How to Evaluate Mitochondria Function?
Naïg Gueguen, Mitovasc Institute, Centre Hospitalier Universitaire d'Angers, France

Workshop 2: Mitochondria Transplantation: From Theoretical to Clinical Applications
Andrés Caicedo, Universidad San Francisco de Quito, Ecuador


Day 2 - Thursday, October 23, 2025

Congress Sessions 

Targeting Mitochondria 2025 Keynote Speech
•⁠ Nick Lane – Mitochondria and the Meaning of Life

Session 1: Mitochondrial Dynamics in Health and Diseases: Mechanistic and Perspectives


•⁠  ⁠Marc Germain – Actin Dynamics In Mitochondrial Function: Implications For Cellular Homeostasis And Disease
•⁠  ⁠Yosuke Togashi – Immune Evasion through Tumor-Derived Mitochondrial Transfer
•⁠  ⁠Florent Waltz – How Mitochondria Organize Their Powerhouse Machinery for Optimal Performance
•⁠  ⁠Edmund Kunji – Targeting Mitochondrial Pyruvate Carrier: Impact on Future Metabolic Therapies
•⁠  ⁠Luca Gattinoni – Fighting Fire with Fire: Boosting T Cell Therapy by Intercellular Mitochondrial Transfer
•⁠  ⁠Joanna Rorbach – Mitochondrial Protein Synthesis: A Key on Health and Disease / Mitoribosomes and Disease
•  Tatjana Kleele – Mitochondrial Dynamics: Steering the Future of Mitochondrial Remodeling in Health and Disease

Short oral presentations

Session 2: Advances in Mitochondria: Insights, Debates, and Controversies


•⁠  ⁠Alessandro M. Morelli – Delocalisation of the Macromolecular Devices for Efficient ATP Synthesis in Extra-Mitochondrial Districts

 


Day 3 - Firday, October 24, 2025

Congress Sessions 

Targeting Mitochondria 2025 Keynote Speech
•⁠  ⁠Adam Szewczyk – Targeting Mitochondrial Channels: Update and Strategies


Session 3: Emerging Trends and Innovations in Mitochondria Research


•⁠  ⁠Alessandro Prigione – Brain Organoids for Drug Discovery of Mitochondrial Neurological Disorders
•⁠  ⁠David Rizo Roca – Mitochondria and Creatine: Perspectives and Strategies
•⁠  ⁠Alberto Anel – Mitochondrial Cybrids: Advancing Precision Oncology
•⁠  ⁠Ayumu Sugiura – The Role of Mitochondrial-Derived Vesicles in Peroxisome Biogenesis
 

Session 4: Mitochondria medicine: Strategies to Target Mitochondria, Clinical Trials and Potential Mitochondria-Based Therapies


•⁠  ⁠Volkmar Weissig – Drug Development for the Therapy of Mitochondrial Diseases
•⁠  ⁠Kosuke Kusamori – Development of Mitochondria-Based Therapeutic Strategies for Disease Treatment
•⁠  Gökhan Burçin Kubat – Mitochondrial Transplantation: From Skeletal Muscle Atrophy to Human Clinical Advances and Perspectives
•⁠  Andrés Caicedo - Mitochondria Transplantation: From Theoretical to Clinical Applications

Short Communications:

MNRR1-dervied peptides, a promising therapeutic target for mitochondrial dysfunction syndromes
Lawrence Grossman, Wayne State University, USA

Targeting Mitochondria 2025 Awards 

WMS Concluding Remarks

Abstracts Submission 2025 Now Open

 save the date

Short Oral Deadline: September 30, 2025

Poster Deadline: October 9, 2025

Buttons-registrationButtons-abstract-submission
 

Mitochondria in the Press & Media