Monitoring mitochondrial oxygenation and oxygen consumption: first clinical experiences

One of the session of Targeting Mitochondria 2016 is dedicated to "How to evaluate mitochondrial function/dysfunction?". This session will be organized during the second day of the congress.

Pr Egbert Mik from Erasmus MC, Netherlands will be one of the major speaker of this strategic session. He will present the first clinical experiences related to monitoring mitochondrial oxygenation and oxygen consumption.

Marvin Edeas & Volkmar Weissig asks to Egbert Mik to highlight the following key points:

• How to measure mitochondrial oxygenation and oxygen consumption in vivo?
• Is monitoring at the sub-cellular level feasible in clinic?
• How will mitochondrial measurements affect patient care?

If you are interested to know more about this technic, don't hesitate to register on www.targeting-mitochondria.com  

Marvin Edeas / Volkmar Weissig / Chairmen of WMS 

What is the role of mitochondrial ROS in neutrophil-mediated inflammation and autoimmunity?

Dr Christian Lood from the University of Washington, USA was invited by the scientific committee of Targeting Mitochondria Congress to present his recent data related to the role of mitochondrial ROS in neutrophil-mediated inflammation and autoimmunity.

Marvin Edeas and Volkmar Weissig, chairmen of the conference, stated: "Dr Lood will present some of the recent data on the role of mitochondria in neutrophil-mediated inflammation and autoimmunity. In particular, he will highlight the following points:

- role of mitochondrial ROS in induction of neutrophil programmed necrosis, neutrophil extracellular trap (NET) formation, and its implications in autoimmunity such as vasculitis and systemic lupus erythematosus (SLE)

- how released mitochondrial DNA may confer inflammation through the recently described DNA-sensing cGAS-STING pathway

- description of some potential approaches to limit mitochondrial-mediated damage in SLE"

If you are interested to know more about mitochondria, inflammation and autoimmunity, don't hesitate to register to Targeting Mitochondria 2016: www.targeting-mitochondria.com

Marvin Edeas / Volkmar Weissig / Chairmen of WMS

Mitochondrial protein import defect in Huntington’s disease will be highlighted by Robert Friedlander

Dr. Robert Friedlander, chairman Department of Neurological Surgery from UPMC Presbyterian Hospital, Pittsburgh, USA was invited by Marvin Edeas and Volkmar Weissig to talk about:

• Role of mitochondrial protein import in Huntington's disease
• Site specific mitochondrial vulnerability.
• Interaction of mutant huntington with TIM23

For more information: www.targeting-mitochondria.com

Marvin Edeas / Volkmar Weissig / Chairmen of WMS

Pr Vladimir Skulachev talked about prolongation of youth by delay of ontogenesis (neoteny) or by a mitochondria-targeted antioxidant

Pr Vladimir Skulachev from the University of Moscow, Russia was invited by the scientific committee of the 7th World Congress on Targeting Mitochondria to present his recent resultats of the clinical trial done with SkQ1.

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Organize a meeting with the leaders in mitochondria field

Targeting Mitochondria attendees, academics and industrials, are invited to a warm-up networking session over the lunch and coffee breaks. Already more than 300 registrants!

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Daniel Schniertshauer was awarded for his poster presentation during Targeting Mitochondria 2016

At the end of Targeting Mitochondria World Congress, Pr Volkmar Weissig and Pr Marvin Edeas awarded two scientists for their research. Among them:

	Daniel Schniertshauer from the Albstadt-Sigmaringen University of Applied Sciences, Germany for his poster presentation about "Accelerated Regeneration of ATP Level after Irradiation in Human Skin Fibroblasts by Coenzyme Q10". You can download his poster by clicking here.
Testimonial by Dr Schniertshauer: "The 7th World Congress on Targeting Mitochondria was the second time I was allowed to attend this conference after 2015. The participation of several hundred participants from all over the world at the last congress showed me the importance of this event in the research community of mitochondria. As last year, I was already looking forward to the most diverse presentations, the nice conversations with colleagues and the establishment of contacts between the lectures. In addition, the daily poster sessions were excellent for picking up the one or the other piece of advice from experienced colleagues. It was inspiring to see how researchers with a wide range of topics are interested in the current research, exploring them and are interested in the contributions of the other presenters. For me this was living science! I think, not only for young doctoral students, the visit of such a congress is highly recommended, because through the diversity of topics you get insights into other areas of mitochondrial research and thus you can look beyond the box. The aim of such an event should be to make the knowledge of current themed lectures tangible for your own research. I'm really looking forward to the next Targeting Mitochondria."
	François Mouton-Liger from the ICM - Brain & Spine Institute, France for his short oral presentation about "Role of Parkin in innate immunity: crosstalk between mitochondrial dysfunction and NLRP3 inflammasome signaling".
Testimonial by Dr Mouton-Liger: "Understanding mechanisms by which mitochondrial dysfunction contributes to the pathophysiological processes of neurodegenerative disorder, in particular Parkinson disease, will need in the future an integrated vision of all mitochondrial aspects from emerging methods to evaluate mitochondria function to new molecular interactions link to this organelle. By this way, the 7th World Congress on Targeting Mitochondria was, for me, a huge success by connecting remarkable researchers from such different area of the field, For these reasons, it will be a great pleasure for me to participate to this conference next year."

The second award was discerned to François Mouton-Liger from the ICM - Brain & Spine Institute, France for his short oral presentation about "Role of Parkin in innate immunity: crosstalk between mitochondrial dysfunction and NLRP3 inflammasome signaling".

For more information about this award, please click here.

World Mitochondria Society

The award for the short oral presentation was discerned to François Mouton-Liger

At the end of Targeting Mitochondria World Congress, Pr Volkmar Weissig and Pr Marvin Edeas awarded two scientists for their research. Among them:

François Mouton-Liger from the ICM - Brain & Spine Institute, France for his short oral presentation about "Role of Parkin in innate immunity: crosstalk between mitochondrial dysfunction and NLRP3 inflammasome signaling".

Testimonial by Dr Mouton-Liger: "Understanding mechanisms by which mitochondrial dysfunction contributes to the pathophysiological processes of neurodegenerative disorder, in particular Parkinson disease, will need in the future an integrated vision of all mitochondrial aspects from emerging methods to evaluate mitochondria function to new molecular interactions link to this organelle. By this way, the 7th World Congress on Targeting Mitochondria was, for me, a huge success by connecting remarkable researchers from such different area of the field, For these reasons, it will be a great pleasure for me to participate to this conference next year."

The second award was discerned to Daniel Schniertshauer from the Albstadt-Sigmaringen University of Applied Sciences, Germany for his poster presentation about "Accelerated Regeneration of ATP Level after Irradiation in Human Skin Fibroblasts by Coenzyme Q10". 

For more information about this award, please click here.

World Mitochondria Society

Pr Marvin Edeas and Pr Volkmar Weissig commented the 7th World Congress on Targeting Mitochondria 2016

The 7th World Congress on Targeting Mitochondria was organized in Berlin on October 24-26, 2016. This seventh edition was again a huge success and gathered more than 350 attendees, academics, industrials and start-ups during three days, representing more than 27 countries.

The scientific committee validated more than 170 communications (oral and poster) which have highlighted the recent scientic advances on mitochondria and all related researches such as the methods to evaluate mitochondria function/dysfunction, but also new strategies to target the mitochondria. To access to the final program of the congress, please follow this link.

Pr Volkmar Weissig, from the Midwestern University commented: “As President of the WMS I am extremely happy about the success of our 7th World Conference on Targeting Mitochondria. I would like to personally thank the organizing team for the excellent work they have done in planning and setting up this conference. Of course, any conference is just as good as its participants. Therefore I sincerely thank all invited speakers, all presenters of short oral communications and all poster presenters for their excellent contributions. I also would like to thank all other attendees for participating in our conference. Our conference series has over the last years significantly grown with respect to the number of registrations. With over 310 participants from almost all continents we have set a new a record. I believe our conference series has established itself as a major event in the international “mitochondrial landscape”. If I may say so, mitochondria have found a home in Berlin! With excitement I am already looking forward to the 8th edition next year and I sincerely hope to see most if not all of you again one year from now.”

From his side, Pr Marvin Edeas, from Institut Cochin, INSERM U1016, University Paris Descartes commented: "The world of mitochondria is "hyper-dynamic". Mitochondria is a very dynamic organelle, it moves, oscillates and communicates with cells and in particular with microbiota. We need to re-design a "dynamic" strategy to target mitochondria in all its dimensions. This strategy must integrate all factors and actors (microbiota).
Again, as founder of WMS and co-chairman of the scientific committee, I believe that mitochondria-microbiota inter-talk is one of the perfect target to highlight."

To conclude this three-day meeting, the scientific awarded two scientists for their research:

The dates of Targeting Mitochondria 2017 will be announced very soon on the website.

World Mitochondria Society
www.targeting-mitochondria.com