Scientific Award of Targeting Mitochondria 2021

Targeting Mitochondria 2021 Alessandro Prigione AwardAt the end of Targeting Mitochondria 2021, the scientific committee awarded Prof. Alessandro Prigione for his presentation about "Patient-Specific Brain Organoids for Modeling Mitochondrial Diseases"

Alessandro Prigione is a tenured Associate Professor of Pediatric Metabolic Medicine at the Department of General Pediatrics, Neonatology and Pediatric Cardiology at Heinrich Heine University (HHU) in Düsseldorf Germany.

The interest of the Prigione group is to develop induced pluripotent stem cells (iPSC)-based approaches for disease modeling and drug discovery of rare incurable neurological and neurodevelopmental disorders affecting mitochondrial metabolism. A specific focus is on Leigh syndrome, which is the most severe mitochondrial disease affecting children. His latest work (Inak et al Nature Communications 2021) employed human neurons and brain organoids from patients with Leigh syndrome to dissect the neuronal-specific disease mechanisms and led to the identification of novel disease targets and interventions.

Targeting Mitochondria 2021 Congress
October 27-29, 2021 - Interactive Online Congress