Metabolic effects of Cimicfuga racemosa extract on mitochondria and implications for the resistance against oxidative cell death and longevity
Prof. Carsten Culmsee, active member of the scientific committe and from the University of Marburg, Germany, will join Targeting Mitochondria 2023 this October. He will have a talk entitled "Metabolic effects of Cimicfuga racemosa extract on mitochondria and implications for the resistance against oxidative cell death and longevity".
Cimicifuga racemosa extract (CRE) is a well-established herbal medication to treat menopausal symptoms such as hot flashes and weight gain. In contrast to estrogen replacement therapy or phytoestrogens, however, CRE does not act through stimulation of estrogen receptors but through metabolic mechanisms. Prof. Culmsee and his team's findings suggest that CRE Ze 450 rather exerts direct effects on mitochondrial energy turnover through interference with components of the mitochondrial electron transport chain (ETC).
Prof. Culmsee will provide a comprehensive insight into the signalling effects of the extract on the mitochondrial proteome and metabolome, highlighting the role of CREe for the resilience against age-related processes engaging impaired mitochondria and loss of antioxidative capacities.
Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany
