Immune Evasion through Tumor-Derived Mitochondrial Transfer
We are honored to announce that Prof. Yosuke Togashi will present at Targeting Mitochondria 2025. His participation is strategic and timely, following his landmark publication in Nature (Feb 2025), revealing a previously unknown mechanism of immune evasion via mitochondrial transfer in the tumor microenvironment.
Summary
Prof. Togashi will highlight their recent findings on how cancer cells evade immune responses by transferring mitochondria to tumor-infiltrating lymphocytes (TILs). The presentation will explore key mechanisms linking mitochondrial transfer, immune suppression, and TIL dysfunction in the tumor microenvironment.
Prof. Yosuke Togashi earned his M.D. from Kyoto University School of Medicine in 2006 and initially worked as a clinician in the Department of Respiratory Medicine. After serving as an Assistant Professor at Kyoto University, he obtained his Ph.D. in Genome Biology at Kindai University in 2015. His early career was distinguished by a research fellowship at the Japan Society for the Promotion of Science. He subsequently began basic and translational research in cancer immunology as a postdoctoral fellow at the National Cancer Center (Nishikawa Lab) in 2016. Since 2021, he has been a Professor at Okayama University, focusing on translational research of the tumor microenvironment. Additionally, he has been a Professor at OKAYAMA UNIVERSITY HOSPITAL, Department of Allergy and Respiratory Medicine, since 2024.
