WMS is happy to welcome Prof. Eric Schon from Columbia University, USA, as a keynote speaker on Day 1 of Targeting Mitochondria 2024 in Berlin this October.
Prof. Schon will deliver a presentation titled "Mitochondria in Alzheimer disease: it's not what you think"
The dominant hypothesis of Alzheimer disease (AD) pathogenesis invokes the accumulation of a cleavage product of the amyloid precursor protein (APP), called beta-amyloid, as the driver of pathogenesis. However, the poor track record of clinical trials based on this hypothesis suggests that other causes likely underlie the disease. We propose an alternative hypothesis in which a different APP cleavage product, called C99, is the main culprit, via its role as a regulator of cellular cholesterol metabolism. In AD, both C99 production and cellular cholesterol levels are increased well above normal levels, resulting in essentially all of the biochemical and clinical features of the disease. From this perspective, AD is, at bottom, a lipid disorder.
About Eric Schon
Eric Schon, a professor of Neurology and Genetics, has focused on the intricacies of mitochondrial genetics, highlighting their unique semi-autonomous nature governed by both nuclear and mitochondrial DNA. Mitochondria, once bacteria, contribute to cellular energy production through oxidative phosphorylation. Schon's research explores various inherited and sporadic mitochondrial disorders, employing innovative techniques like cytoplasmic hybrids. Recently, his focus shifted to Alzheimer's disease, uncovering heightened ER-mitochondrial communication as a potential key player in its pathogenesis, offering insights into diagnosis and treatment.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
It is with great pleasure that we welcome Prof. Howy Jacobs from Tampere University, Finland, as a keynote speaker on Day 2 at Targeting Mitochondria 2024 in Berlin this October.
Prof. Jacobs has documented "A century of mitochondrial research, 1922–2022" in the Enzymes Book Series (2023). The chapter discussed the comprehensive research history of mitochondria, starting from their initial recognition as resembling bacteria in 1922, to their integration into cell physiology today, highlighting major advances in various scientific fields such as biochemistry, genetics, pathology, and cell biology.
Keynote Speech: "Mitochondria: More Heat Than Light?"
"Mitochondria are not just producers of ATP or clearing houses of intermediary metabolism. Here I will trace the history of how mitochondria have come to be regarded as key contributors to cell and organismal physiology, and how recent findings have opened up new chapters in our thinking" stated Prof. Jacobs.
Prof. Jacobs will discuss the implications of elevated mitochondrial temperature for evolution, development, cell signaling, immunity and pathology.
© Photo Credits: Rami Hanafi
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
]]>
Prof. Stefano Pluchino, University of Cambridge, United Kingdom, will be joining Targeting Mitochondria 2024 this October in Berlin.
Prof. Pluchino will be sharing his latest research on the role of mitochondrial extracellular vesicles in brain plasticity and recovery, during the session dedicated to "Emerging Trends and Strategies in Mitochondria Research".
In his talk Prof. Pluchino will cover the the following:
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
]]>
Dr. Devika S Manickam, Duquesne University, USA, and active member of the WMS Scientific Committee will be joining Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Mitochondria Delivery via Extracellular Vesicles to the Blood-Brain Barrier
Highlights
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
It is a great pleasure to welcome Dr. Mark Kindy, MitoSense, USA, at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Mitochondria Iron Metabolism: Mitochondrial Transplantation Mediates Improved Cellular Energy Metabolism, Restoration of Mitochondrial Function and Prevention of Cell Death
In his talk Dr. Kindy will cover:
Targeting Mitochondria 2024 program.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
]]>
It is a great pleasure to welcome Dr. Antentor Hinton, Vanderbilt University, USA, at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Cracking the Code of Aging: Exploring Mitochondrial Dynamics and Organelle Connections.
Highlights
More information on Dr. Hinton's latest research.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
It is a great pleasure to welcome Dr. Indira Mysorekar, Baylor College of Medicine, USA, at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: The Role of Mitochondria in Zika Virus Propagation: Mechanisms of Immune Evasion and Inter-Cellular Transmission.
Highlights
More information on Dr. Mysorekar's latest research.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
Prof. Naotada Ishihara, Osaka University, Japan, will be joining Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Dynamics of Mitochondria: Regulation of Nucleoid Morphology to Protect Mitochondrial Function.
Highlights
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
It is a great pleasure to welcome Dr. Giulia Bertolin, Université de Rennes, France, at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: New Biosensing Solutions and Optimized Pharmacological Inhibitors to Counteract Mitophagy in Cancer Cells
Highlights
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
It is a great pleasure to welcome Dr. Ana Andreazza, University of Toronto, Canada at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Mitochondrial Dynamics in Health and Disease: Advances in Mood Disorders and Mitochondrial-Organ Transplantation
Points to be covered:
1. Mitochondrial Dynamics in Health and Disease:
Explore the essential role of mitochondria in energy balance, neuronal signaling, and cellular health. Emphasize their influence on the brain and other critical organs, underlining the importance of mitochondrial health in overall bodily function.
2. Linking Mitochondrial Dysfunction to Mood Disorders:
Explore the relationship between mitochondrial dysfunction and mood disorders. Present clinical evidence showing their correlation and introduce cutting-edge mitochondrial-targeted metabolomics to improve patient classification and treatment paths.
3. Innovative Therapeutic Approaches:
Discuss advancements in mitochondrial transplantation and the creation of the MitoGENE risk score. These innovations aim to refine diagnostic and therapeutic strategies, supported by data from real-world clinical trials.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
Prof. Maik Hüttemann, Wayne State University, USA, and active member of the WMS Scientific Committee will be joining Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Mitochondria and Photomedicine: Advances in Infrared Light Treatment.
Highlights
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
It is a great pleasure to welcome Dr. Sonia Levi, Vita-Salute San Raffaele University, Italy, at Targeting Mitochondria 2024 this October in Berlin.
Presentation title: Mitochondria Iron Metabolism: Its Role in Pathogenesis of Diseases
In her talk Dr. Levi will cover the following:
More information on Dr. Mysorekar's latest research.
World Mitochondria Society
Annual World Congress on Targeting Mitochondria
LinkedIn | Facebook
We have the pleasure to announce the formation of the WMS Task Force, a groundbreaking initiative committed to driving innovation and reshaping the landscape of mitochondria research in health and diseases.
The Aim of WMS Task Force
Through the establishment of a cooperative environment, this Task Force aims to address the challenges that impede the understanding, prevention and treatment of diseases related to mitochondria. It is a platform where knowledge and expertise are freely shared, fostering an atmosphere conducive to significant advancements in mitochondria research in health & diseases.
Our vision of establishing a Task Force that brings together multidisciplinary experts, which is crucial for pushing the boundaries of mitochondrial research and innovation. By fostering a collaborative environment, we can collectively address challenges, share knowledge and expertise, and drive advancements in the understanding of mitochondria research and related diseases.
WMS Task Force Projects
The WMS Task Force is launching 2 projects for the improvement of mitochondrial research and applications:
1- Mitochondrial Transfer & Tunneling Nanotubes (TNTs). Read more.
2- Mitochondrial Oscillation and Resonance: Impact on ATP Production and Distribution in Health and Diseases. Read more.
The Funding
In terms of funding, the WMS Task Force is prepared to submit the selected projects to both public and private institutions. The objective is to secure the necessary resources to fuel these projects, and ensure the sustainability and longevity of the task force.
The collected funding will be distributed to all teams invovled in the Task Force.
How to Join the Task Force & Structure your Project Proposal?
To contribute to one of these 2 pioneering projects, the WMS requests interested researchers and teams to submit a proposal detailing the following aspects:
· Project Overview:
Please provide a concise description of your current research or project. Include key goals, methodologies used, and any preliminary results or findings that could highlight the relevance and potential impact of your work.
· Alignment with Task Force Goals:
Articulate how your work contributes to the broader objectives of the task force. This could be in terms of techniques being developed, the specific aspects of mitochondrial transfer your project focuses on, or the potential applications of your research.
· Challenges and Solutions:
Identify any potential hurdles or obstacles you anticipate in the course of your research. This could be technical issues, logistical constraints, or theoretical problems. Additionally, provide an outline of how you propose to tackle these challenges. This shows proactive problem-solving and can help us better understand the feasibility of your project.
· Team Profile:
Furnish an overview of your team and its expertise. Highlight the skills, qualifications, and experiences of your team members that make them well-equipped to carry out the proposed project. Include any past achievements or relevant projects that demonstrate your team’s capacity to successfully execute the research.
How to Submit?
Please submit your projects and details above to:
· Prof. Volkmar Weissig, President of the WMS
· Prof. Marvin Edeas, Chairman of the Scientific Committee
- At the following email address: mitochondria(at)wms-site.com.
- Deadline for the submission: June 30, 2024.
Applications will be reviewed by the Task Force Selection Committee, and successful applicants will be contacted to proceed to the next stage of the process. Please note that acceptance into the task force is competitive, and only a select number of applicants will be chosen to join.
We look forward to your valuable input and collaboration in this groundbreaking endeavor.
World Mitochondria Society
Targeting Mitochondria Congress
]]>
The 15th World Congress on Targeting Mitochondria on October 29-31, 2024 in
DoubleTree by Hilton Berlin Ku'damm
Los-Angeles-Platz 1
10789 Berlin, Germany
Book your Hotel with a Reduced Price
Attendees of Targeting Mitochondria 2024 can benefit from discounted room booking rates at the DoubleTree by Hilton Berlin Ku'damm Hotel.
King Guest Room: 209€ per night, inclusive of VAT and breakfast.
Important note: The rooms are limited in quantity. The offer is valid until September 13, 2024.
How To Access
1. From Berlin Tegel Airport (TXL):
2. From Berlin Schönefeld Airport (SXF):
3. By Train from Berlin Hauptbahnhof:
4. By Car:
5. Public Transportation:
World Mitochondria Society
15th Targeting Mitochondria 2024 Congress
October 29-31, 2024 - Berlin, Germany
www.wms-site.com
Dr. Marvin Edeas, Institut Cochin, INSERM U1016, Université Paris Cité, France, is pleased to invite Dr. James McCully of Harvard Medical School and Boston Children's Hospital to present a talk dedicated to Mitochondrial Transplantation, both online and in Paris.
The focus of the Dr. McCully's talk will be on "Mitochondrial Transplantation: Rescue of Cellular Viability and Function and Modulation of the Ischemic Phenotype in the Myocardium".
Dr. McCully will discuss the role of mitochondrial transplantation in improving outcomes for myocardial ischemia/reperfusion injury and its effects on the transcriptomic profile.
You are all cordially invited to join us.
World Mitochondria Society
Practical Information
Date & Venue
The webinar is scheduled for Friday, March 22, 2024, from 3:00 PM to 5:15 PM Paris time.
Participants can choose to attend the event in two ways:
Registration & Participation
There is no fee to attend this webinar, but space is limited. Interested individuals are encouraged to register early to ensure participation.
Why did Dr. Marvin Edeas invite Dr. James McCully to host a webinar on Mitochondrial Transplantation?
Dr. McCully plays a strategic role in the field of medicine, especially his groundbreaking work in pediatric cardiac surgery and his development of mitochondrial transplantation. Dr. McCully has dedicated his career to innovating treatment approaches for congenital heart conditions, significantly improving outcomes for pediatric patients. His research has not only advanced surgical procedures but also introduced new technologies to enhance the quality of life for children with heart defects.
The technique of mitochondrial transplantation, pioneered by Dr. McCully, represents a major advancement in medical science, offering a novel method to deliver healthy mitochondria directly to damaged tissues, thus rescuing organ function. This innovation, first applied at Boston Children's Hospital in 2014, has shown that mitochondrial transplantation can safely and effectively restore injured heart muscle, even in critical cases.
Given Dr. McCully's extensive publication record, with 234 papers and 13 patents, and his involvement in leading scientific associations, his expertise and contributions are highly valued by the medical community. His work aligns closely with the interests of the World Mitochondria Society, making him an ideal candidate to share insights on the therapeutic efficacy of mitochondrial transplantation in treating myocardial ischemia/reperfusion injury and its potential for broader applications in medicine.
]]>
Join us in Berlin from October 29-31, 2024, for the 15th World Congress on Targeting Mitochondria.
Targeting Mitochondria 2024: New Visionary Approaches
The President of the World Mitochondria Society, Volkmar Weissig, and the Chairman of the Scientific Board, Marvin Edeas, have highlighted the complexities involved in curating an agenda and identifying suitable speakers as significant challenges. In response, they are adopting a progressive and "out of the box" perspective.
Volkmar Weissig and Marvin Edeas aim to take an unconventional approach by concentrating on Emerging Trends and Strategies in mitochondrial research. To this end, they have selected topics such as exosomes and extracellular vesicles, the application of artificial intelligence, the mitochondria-microbiota interplay, the role of mitochondria in photomedicine, and exploratory discussions on the incorporation of Chinese medicine principles.
Summary of the Agenda
Day 1 - Tuesday, October 29, 2024: Mitochondria Workshop
Day 2 - Wednesday, October 30, 2024: Keynote and Sessions
Keynote Presentation: “The Mitochondrial Kingdom: Historical Moments, Evolutionary Insights, Current Understanding, and Future Projections.”
Session 1: Mitochondrial Biodynamics in Health and Diseases
Session 2: Evaluation and Quality Control of Mitochondrial Function
Day 3 - Thursday, October 31, 2024: Continuing Sessions and Concluding Remarks
Session 3: 15th World Mitochondria Society Meeting on Emerging Trends and Strategies
Session 4: Mitochondrial Medicine 2024: From Bench to Bedside
Concluding Remarks & Awards:
It will be a great pleasure to meet you in Berlin next October for this exciting congress!
Sincerely,
Prof. Volkmar Weissig
President of the World Mitochondria Society
Midwestern University, USA
On behalf of the WMS Scientific Board
]]>
The World Mitochondria Society has scheduled an annual workshop on the Evaluation of Mitochondrial Function, led by Dr. Naig Gueguen, for October 29 in Berlin, preceding the Targeting Mitochondria 2024 conference.
Aims & Objectives
Intended Audience
Post-Workshop Materials
WMS 2024 Workshop: Topics & Sessions
Session 1: Bioenergetics
Session 2: Biogenesis, Dynamics, and Mitophagy
Session 3: Practical Insights into Mitochondrial Function
Dr. Naig Gueguen, affiliated with the Mitovasc Institute, Mitolab team, INSERM 1083, CNRS 6215, at the Centre Hospitalier Universitaire d’Angers, Angers, France, leads the workshop.
World Mitochondria Society
Targeting Mitochondria 2024 Congress
October 29-31, 2024 - Berlin, Germany
LinkedIn | Facebook
]]>
Dr. Naig Gueguen from the Mitovasc Institute has been recognized with the coveted 2023 Best Scientific Contribution Award, a testament to her role as a trailblazing scientist in the field.
In her excellent workshop titled "How to Evaluate Mitochondrial Function," Dr. Gueguen, affiliated with INSERM 1083, CNRS 6215, and Centre Hospitalier Universitaire d’Angers, showcased the depth of her expertise.
She navigated through the nuances of mitochondrial study, touched on key technological tools, delved into critical markers, elucidated diverse techniques for examination, presented diagnostic approaches, and shared invaluable case studies centered on mitochondrial anomalies.
The WMS extends its heartfelt congratulations to Dr. Gueguen for her stellar contributions and presentation.
Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany
wms-site.com
Targeting Mitochondria 2023 Best Short Oral Presentation Award #2
The World Mitochondria Society celebrates Sami Noujaim from the University of South Florida, USA, for clinching the Targeting Mitochondria 2023 Best Short Oral Presentation Award.
Dr. Noujaim's insightful talk, "Mitochondrial Involvement in Cardiac Electrophysiological Injury Due to Inhalation Exposure to Electronic Nicotine Delivery Systems (ENDS)," delved into the alarming effects of vaping on heart electrophysiology.
He expertly highlighted the role of adverse mitochondrial changes and increased oxidative stress in these effects.
All our congratulations.
Targeting Mitochondria 2023 Congress
October 11-13, 2023 - Berlin, Germany
wms-site.com